• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: SOX{8,9,10}.p2

Z-value: 1.580

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_+_52665196	1.828	NM_017409	HOXC10	homeobox C10
chr9_+_123501186	1.725		DAB2IP	DAB2 interacting protein
chr7_+_2638156	1.661		TTYH3	tweety homolog 3 (Drosophila)
chr2_+_232281491	1.639		PTMA	prothymosin, alpha
chr20_-_38751289	1.587	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr3_-_11598829	1.583	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr12_-_120725210	1.494		LOC338799	hypothetical LOC338799
chr3_-_187309442	1.481	NM_004454	ETV5	ets variant 5
chr2_+_232281470	1.420	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr1_-_32574185	1.363	NM_023009	MARCKSL1	MARCKS-like 1
chr11_+_20005704	1.355		NAV2	neuron navigator 2
chr9_+_115303527	1.314	NM_130795	RGS3	regulator of G-protein signaling 3
chr1_+_43539239	1.278	NM_005424	TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_-_27171673	1.248	NM_152739	HOXA9	homeobox A9
chr17_+_75366524	1.232	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr7_+_2638108	1.213	NM_025250	TTYH3	tweety homolog 3 (Drosophila)
chr1_-_2451543	1.200	NM_001010926	HES5	hairy and enhancer of split 5 (Drosophila)
chr6_+_30796064	1.175		TUBB	tubulin, beta
chr1_+_158636987	1.171	NM_020335	VANGL2	vang-like 2 (van gogh, Drosophila)
chr6_+_43565192	1.149	NM_001146017	TJAP1	tight junction associated protein 1 (peripheral)
chr1_-_152431175	1.118	NM_152263	TPM3	tropomyosin 3
chr1_+_32992131	1.110
chr14_+_62740878	1.078	NM_020663	RHOJ	ras homolog gene family, member J
chr5_+_40877053	1.076	NM_032587	CARD6	caspase recruitment domain family, member 6
chr7_-_27171648	1.069		HOXA9	homeobox A9
chr6_+_114285209	1.038	NM_002356	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr18_-_13905534	1.033	NM_000529	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)
chr17_-_46479127	1.028		SPAG9	sperm associated antigen 9
chr19_+_59333287	1.020		CNOT3	CCR4-NOT transcription complex, subunit 3
chr17_+_34115383	1.008	NM_005937	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_-_1772305	1.005		SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr7_-_27171600	0.995		HOXA9	homeobox A9
chr19_+_59333232	0.967	NM_014516	CNOT3	CCR4-NOT transcription complex, subunit 3
chr7_-_5429702	0.952	NM_001080495	TNRC18	trinucleotide repeat containing 18
chr4_-_185963859	0.937		ACSL1	acyl-CoA synthetase long-chain family member 1
chr7_+_148613304	0.935		LOC155060	AI894139 pseudogene
chr10_+_6284845	0.933	NM_004566	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr3_-_46879883	0.928	NM_000258	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow
chr22_+_38652555	0.921		GRAP2	GRB2-related adaptor protein 2
chr1_+_15957832	0.920	NM_017556	FBLIM1	filamin binding LIM protein 1
chr1_+_29113589	0.908	NM_001166006	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr7_+_142270634	0.884		EPHB6	EPH receptor B6
chr16_-_30841938	0.884		NCRNA00095	non-protein coding RNA 95
chr10_+_73703682	0.880	NM_019058	DDIT4	DNA-damage-inducible transcript 4
chr11_+_66764060	0.876		LOC100131150	hypothetical protein LOC100131150
chr7_+_73341640	0.864	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr17_+_56843893	0.858	NM_203425	C17orf82	chromosome 17 open reading frame 82
chr3_-_158704056	0.848	NM_001167915 NM_001167916	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chr11_+_66764064	0.833		KDM2A	lysine (K)-specific demethylase 2A
chr6_+_7671267	0.832		BMP6	bone morphogenetic protein 6
chr6_-_139654807	0.821	NM_153235	TXLNB	taxilin beta
chr19_+_44595589	0.801	NM_022835	PLEKHG2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_+_107433179	0.798	NM_007076	FICD	FIC domain containing
chr1_+_246178701	0.794	NM_001001963	OR2L8	olfactory receptor, family 2, subfamily L, member 8
chr7_+_128136347	0.775		FAM71F1	family with sequence similarity 71, member F1
chr4_+_37655385	0.774		TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr6_+_30796123	0.772	NM_178014	TUBB	tubulin, beta
chr3_+_188131209	0.769		ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr1_-_12599934	0.768	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr7_+_149707338	0.755	NM_173680	ZNF775	zinc finger protein 775
chr6_+_29799095	0.746	NM_001098478 NM_001098479 NM_018950	HLA-F	major histocompatibility complex, class I, F
chr19_+_60543032	0.745	NM_032701	SUV420H2	suppressor of variegation 4-20 homolog 2 (Drosophila)
chr1_-_6402467	0.743	NM_019089	HES2	hairy and enhancer of split 2 (Drosophila)
chr19_+_63482118	0.742	NM_021089	ZNF8	zinc finger protein 8
chr15_-_39973566	0.740	NM_016642	SPTBN5	spectrin, beta, non-erythrocytic 5
chr8_-_38324809	0.727		WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1
chr16_+_1772929	0.724	NM_012225	NUBP2	nucleotide binding protein 2 (MinD homolog, E. coli)
chr6_+_29799182	0.720		HLA-F	major histocompatibility complex, class I, F
chr3_+_49482474	0.716	NM_001165928 NM_001177634 NM_001177635 NM_001177636 NM_001177637 NM_001177638 NM_001177639 NM_001177640 NM_001177641 NM_001177642 NM_001177644 NM_004393	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr5_+_76047536	0.711	NM_001992	F2R	coagulation factor II (thrombin) receptor
chr16_-_65774904	0.706		KIAA0895L	KIAA0895-like
chr3_-_150422474	0.706	NM_000096	CP	ceruloplasmin (ferroxidase)
chrX_+_15428820	0.703	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr17_+_23670247	0.694	NM_014573	TMEM97	transmembrane protein 97
chr1_+_39647762	0.694	NM_015038	KIAA0754	KIAA0754
chr6_+_30796121	0.684		TUBB	tubulin, beta
chr5_+_149960820	0.684	NM_001166208	SYNPO	synaptopodin
chr3_-_158703821	0.681	NM_001167911 NM_001167912	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chr17_+_24598000	0.680	NM_005208	CRYBA1	crystallin, beta A1
chr17_-_70901303	0.672		GRB2	growth factor receptor-bound protein 2
chr11_+_66915997	0.670	NM_004584	RAD9A	RAD9 homolog A (S. pombe)
chr22_+_21852911	0.669		BCR	breakpoint cluster region
chr18_+_3437607	0.664	NM_173207	TGIF1	TGFB-induced factor homeobox 1
chr12_-_51173238	0.664	NM_005554	KRT6A	keratin 6A
chr17_-_35017691	0.663	NM_006160	NEUROD2	neurogenic differentiation 2
chr7_-_96489884	0.662
chr14_-_94306104	0.662	NM_173849	GSC	goosecoid homeobox
chr17_+_24944605	0.656	NM_152345	ANKRD13B	ankyrin repeat domain 13B
chr10_+_99069007	0.653	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr17_-_35017650	0.647		NEUROD2	neurogenic differentiation 2
chr17_+_37373195	0.640
chr3_-_150533948	0.638	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr11_+_60448487	0.637	NM_017870 NM_178031	TMEM132A	transmembrane protein 132A
chr11_-_69228286	0.635	NM_005117	FGF19	fibroblast growth factor 19
chr7_-_27108826	0.624	NM_006735	HOXA2	homeobox A2
chr2_+_172658453	0.623	NM_001038493 NM_178120	DLX1	distal-less homeobox 1
chr12_+_52634950	0.622	NM_173860	HOXC12	homeobox C12
chr6_+_43247179	0.617		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr16_-_1772577	0.617	NM_080861	SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr1_+_153846602	0.616	NM_018116	MSTO1	misato homolog 1 (Drosophila)
chr21_-_31853160	0.613	NM_003253	TIAM1	T-cell lymphoma invasion and metastasis 1
chr15_+_82945223	0.608	NM_001007072 NM_017894 NM_181877	ZSCAN2	zinc finger and SCAN domain containing 2
chr6_-_10523424	0.602	NM_003220	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr22_-_41672990	0.602	NM_007229	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr11_+_71524403	0.601	NM_000804	FOLR3	folate receptor 3 (gamma)
chr17_-_1195096	0.599		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr19_+_53664276	0.596	NM_004228 NM_017457	CYTH2	cytohesin 2
chr6_+_43247168	0.595		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr1_-_16033866	0.595
chr11_-_27450808	0.594	NM_018490	LGR4	leucine-rich repeat containing G protein-coupled receptor 4
chr17_-_1359745	0.592		INPP5K	inositol polyphosphate-5-phosphatase K
chr8_-_22044463	0.589	NM_005144 NM_018411	HR	hairless homolog (mouse)
chr6_+_43246897	0.588	NM_003131	SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr12_-_69289889	0.581	NM_002837	PTPRB	protein tyrosine phosphatase, receptor type, B
chr14_+_58725104	0.578	NM_014992	DAAM1	dishevelled associated activator of morphogenesis 1
chr12_+_47498778	0.575	NM_000725	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr1_-_50661716	0.574	NM_032110	DMRTA2	DMRT-like family A2
chr9_+_133259330	0.572		PRRC2B	proline-rich coiled-coil 2B
chr3_-_50340667	0.571	NM_007275	TUSC2	tumor suppressor candidate 2
chr17_-_37196463	0.565	NM_002230 NM_021991	JUP	junction plakoglobin
chr19_-_59476734	0.564	NM_001080978 NM_005874	LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr17_+_78009819	0.564	NM_001083608 NM_012336 NM_031968	NARF	nuclear prelamin A recognition factor
chr16_-_1772572	0.562		SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr8_-_81155564	0.560	NM_001025252	TPD52	tumor protein D52
chr16_+_464844	0.559	NM_001142272	RAB11FIP3	RAB11 family interacting protein 3 (class II)
chr11_-_16380967	0.558	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr11_-_69343128	0.556	NM_005247	FGF3	fibroblast growth factor 3
chr3_+_45611180	0.555	NM_014240	LIMD1	LIM domains containing 1
chr1_+_22107137	0.553		RPL21	ribosomal protein L21
chr16_+_64958060	0.549		CDH5	cadherin 5, type 2 (vascular endothelium)
chr19_-_1543633	0.549	NM_003926	MBD3	methyl-CpG binding domain protein 3
chr16_+_64958025	0.548	NM_001795	CDH5	cadherin 5, type 2 (vascular endothelium)
chr3_-_50340598	0.547		TUSC2	tumor suppressor candidate 2
chr19_+_11510578	0.547	NM_001299	CNN1	calponin 1, basic, smooth muscle
chr17_+_43373887	0.546	NM_018129	PNPO	pyridoxamine 5'-phosphate oxidase
chr19_+_53664386	0.545		CYTH2	cytohesin 2
chr19_+_54872220	0.540		PRMT1	protein arginine methyltransferase 1
chr7_-_104696678	0.539	NM_182691	SRPK2	SRSF protein kinase 2
chr19_+_54872304	0.539	NM_001536 NM_198318	PRMT1	protein arginine methyltransferase 1
chr17_+_34114924	0.539		MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_-_3008162	0.537	NM_021195	CLDN6	claudin 6
chr1_-_153560532	0.536	NM_001039517	C1orf104	chromosome 1 open reading frame 104
chr1_+_34997928	0.534	NM_153212	GJB4	gap junction protein, beta 4, 30.3kDa
chr4_-_40631397	0.533		APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr12_+_47658502	0.532	NM_005430	WNT1	wingless-type MMTV integration site family, member 1
chr11_+_131285747	0.531	NM_001144058 NM_001144059 NM_016522	NTM	neurotrimin
chr1_+_201363458	0.530	NM_000674 NM_001048230	ADORA1	adenosine A1 receptor
chr19_+_12910428	0.529		CALR	calreticulin
chr16_-_88084387	0.528	NM_013275	ANKRD11	ankyrin repeat domain 11
chr3_+_45610357	0.525		LIMD1	LIM domains containing 1
chr22_+_17498320	0.524	NM_053006	TSSK2	testis-specific serine kinase 2
chr19_+_12910391	0.523	NM_004343	CALR	calreticulin
chr1_+_154855709	0.520	NM_021817	HAPLN2	hyaluronan and proteoglycan link protein 2
chr1_+_36394338	0.515	NM_018067	MAP7D1	MAP7 domain containing 1
chr12_+_91620749	0.514	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr17_+_8154280	0.514	NM_173728	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr7_+_4781784	0.510	NM_014855	KIAA0415	KIAA0415
chr1_-_6468108	0.508		PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr4_+_54660954	0.506	NM_133267	GSX2	GS homeobox 2
chr17_-_71017509	0.506	NM_001142643	CASKIN2	CASK interacting protein 2
chr16_+_1773004	0.503		NUBP2	nucleotide binding protein 2 (MinD homolog, E. coli)
chr5_+_149845503	0.503		NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_+_22432344	0.502	NM_001135865	LOC100132247 NPIPL3	nuclear pore complex interacting protein related gene nuclear pore complex interacting protein-like 3
chr16_-_65775326	0.500	NM_001040715	KIAA0895L	KIAA0895-like
chr12_+_111980044	0.498	NM_004416	DTX1	deltex homolog 1 (Drosophila)
chr4_+_87070449	0.497	NM_031305	ARHGAP24	Rho GTPase activating protein 24
chr7_+_150321771	0.495	NM_001160109 NM_001160110 NM_001160111	NOS3	nitric oxide synthase 3 (endothelial cell)
chr9_+_138341752	0.494	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr15_+_72397934	0.491	NM_182791	CCDC33	coiled-coil domain containing 33
chr3_+_14419066	0.490		SLC6A6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr12_+_48047428	0.488		SPATS2	spermatogenesis associated, serine-rich 2
chr5_+_140719773	0.484	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr3_+_14419087	0.483	NM_001134367 NM_001134368 NM_003043	SLC6A6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr9_+_136358134	0.482	NM_002957	RXRA	retinoid X receptor, alpha
chr5_+_140767953	0.481	NM_018926 NM_032100	PCDHGB6	protocadherin gamma subfamily B, 6
chr9_+_94766379	0.480		FGD3	FYVE, RhoGEF and PH domain containing 3
chr16_+_64958086	0.479		CDH5	cadherin 5, type 2 (vascular endothelium)
chr17_+_72376022	0.478	NM_144677	MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr10_+_70748581	0.478	NM_000188	HK1	hexokinase 1
chr3_+_195887903	0.476	NM_153690	FAM43A	family with sequence similarity 43, member A
chr9_+_132990760	0.475	NM_005085	NUP214	nucleoporin 214kDa
chr9_+_124590970	0.471	NM_001001923	OR5C1	olfactory receptor, family 5, subfamily C, member 1
chr5_+_140573692	0.470	NM_018933	PCDHB13	protocadherin beta 13
chr6_-_42527760	0.470	NM_033502	TRERF1	transcriptional regulating factor 1
chr13_+_48923688	0.470	NM_001160308	SETDB2	SET domain, bifurcated 2
chr5_+_140777454	0.469	NM_018927 NM_032101	PCDHGB7	protocadherin gamma subfamily B, 7
chr15_+_80434362	0.468		UBE2Q2P2	ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 2
chr6_+_50789215	0.467	NM_172238	TFAP2D	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr2_-_100088760	0.466		AFF3	AF4/FMR2 family, member 3
chr19_+_12810258	0.463	NM_014975	MAST1	microtubule associated serine/threonine kinase 1
chr17_+_39778191	0.463		GRN	granulin
chr17_-_1478293	0.461		SLC43A2	solute carrier family 43, member 2
chr1_+_12757570	0.461	NM_001080830	PRAMEF12	PRAME family member 12
chr1_+_149299490	0.460		MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr16_+_57091546	0.459		NDRG4	NDRG family member 4
chr6_+_32515596	0.456	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr22_+_48633532	0.455		ZBED4	zinc finger, BED-type containing 4
chr19_+_50196526	0.455	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr19_-_16544188	0.455	NM_024881	SLC35E1	solute carrier family 35, member E1
chr17_+_19930926	0.450	NM_001033553 NM_152904	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.34	2.07e-09	GO:0032502	developmental process
1.38	5.81e-09	GO:0048856	anatomical structure development
1.35	2.54e-08	GO:0007275	multicellular organismal development
1.38	1.25e-07	GO:0048731	system development
1.45	2.50e-07	GO:0048869	cellular developmental process
1.45	4.21e-07	GO:0030154	cell differentiation
1.32	7.46e-07	GO:0016043	cellular component organization
1.31	1.52e-06	GO:0071840	cellular component organization or biogenesis
2.21	1.46e-05	GO:0030029	actin filament-based process
1.35	1.82e-05	GO:0071842	cellular component organization at cellular level
1.17	4.37e-05	GO:0050794	regulation of cellular process
2.25	6.53e-05	GO:0030036	actin cytoskeleton organization
1.46	7.00e-05	GO:0009653	anatomical structure morphogenesis
1.32	7.36e-05	GO:0071841	cellular component organization or biogenesis at cellular level
1.47	7.97e-05	GO:0007399	nervous system development
1.43	1.82e-04	GO:0006996	organelle organization
1.20	1.89e-04	GO:0032501	multicellular organismal process
1.62	3.25e-04	GO:0051128	regulation of cellular component organization
1.15	4.19e-04	GO:0050789	regulation of biological process
1.14	6.71e-04	GO:0065007	biological regulation
1.31	9.65e-04	GO:0010468	regulation of gene expression
1.33	1.05e-03	GO:0051252	regulation of RNA metabolic process
1.32	1.45e-03	GO:0048519	negative regulation of biological process
1.31	2.26e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.85	2.55e-03	GO:0007264	small GTPase mediated signal transduction
1.32	2.90e-03	GO:0006355	regulation of transcription, DNA-dependent
1.32	5.28e-03	GO:0048523	negative regulation of cellular process
1.28	5.41e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29	7.19e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.52	8.66e-03	GO:0048699	generation of neurons
1.46	9.89e-03	GO:0022607	cellular component assembly
1.50	1.16e-02	GO:0022008	neurogenesis
1.08	1.68e-02	GO:0009987	cellular process
1.55	3.36e-02	GO:0030182	neuron differentiation
1.31	3.51e-02	GO:0048513	organ development
1.25	3.53e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.65	4.48e-02	GO:0007010	cytoskeleton organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.21	2.22e-06	GO:0005634	nucleus
1.09	1.61e-04	GO:0044424	intracellular part
1.08	3.77e-04	GO:0005622	intracellular
1.94	2.65e-02	GO:0005911	cell-cell junction
1.08	4.80e-02	GO:0043226	organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.61	1.70e-06	GO:0001071	nucleic acid binding transcription factor activity
1.61	1.70e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.76	6.47e-05	GO:0008092	cytoskeletal protein binding
1.50	4.70e-04	GO:0030528	transcription regulator activity
1.30	1.07e-03	GO:0003677	DNA binding
1.13	1.37e-03	GO:0005515	protein binding
1.55	2.29e-03	GO:0019899	enzyme binding
1.07	1.07e-02	GO:0005488	binding
1.77	1.72e-02	GO:0003779	actin binding
2.26	3.93e-02	GO:0030674	protein binding, bridging
2.20	4.72e-02	GO:0060090	binding, bridging